• This study explored the utility of topically applied polymeric nanoparticle suspensions to target delivery of poorly water-soluble drugs to hair follicles. Several formulations of amorphous drug/...

    Publication
     
  • Amorphous spray dried dispersions (SDDs) have emerged as a broadly applicable technology for the delivery of poorly soluble drug molecules and have proved well suited to dosing in suspension and...

    Webinar
     
  • To address the need for formulations with increased oral bioavailability, Bend Research has developed a patented technology platform based on spray-dried dispersions(SDDs)to enhance the delivery of...

    Tech Brief
     
  • At Bend Research, we believe fundamental scientific understanding is the cornerstone of leading-edge technology development. Our commitment to the gathering and application of this understanding...

    Tech Brief
     
  • A broad range of formulation needs can be addressed with oral mutliparticulate technology available at Bend Research. Pellets, beads, and microspheres with coasted and/or matrix architectures can be...

    Tech Brief
     
  • Pharmaceutical firms often desire to delivery crystalline and solubilized forms of compounds in once- or twice-daily dosing regimes to maximize therapeutic effect and patient compliance. To meet this...

    Tech Brief
     
  • An estimated 25-30% of compounds in early development have poor bioavailability due to low solubility, representing a significant loss in economic and therapeutic opportunity. Because many of these...

    Tech Brief
     
  • Ocular drug delivery presents unique challenges and opportunities. Eye tissues can be accessed directly with relative ease using topical eye drops. However, the loading and ocular absorption of drugs...

    Tech Brief
     
  • Bend Research has developed osmotic-delivery dosage forms that are effective for delivery of many active pharmaceutical ingredients, including those having high solubilities in aqueous solutions....

    Tech Brief
     
  • Bend Research has developed a inhalation drug-delivery platform based on engineered particles. This broadly applicable technology: delivers a high-fraction dose reproducibly, enables delivery of...

    Tech Brief
     
  • At Bend Research, we believe that time and money can be saved -- and the best drugs brought to market -- via rational implementation of delivery technologies and biological models early in the drug-...

    Tech Brief
     
  • Many therapeutically active molecules suffer from mechanism-based or off-target toxicities. An estimated 30% of clinical attrition is due to candidate toxicity or other safety issues, representing...

    Tech Brief
     

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