Improving Drug Retention After Knee Injection

November 15, 2011

Nanoparticles that combine with the knee joint’s lubricating fluid to form a hydrogel could form the basis for extended release delivery of drugs for osteoarthritis, researchers announced. Experimental work suggests that the gels formed by charged polymeric nanoparticles and the synovial fluid could help to improve the retention of drugs after injection,one of the researchers said.