Bioprocess Design and Operation: Enhanced Bioreactor Observability and Process Guidance, New Webinar Hosted by Xtalks

January 21, 2015

TORONTO, ON--(Marketwired - January 21, 2015) - Join the live broadcast on February 10, 2015 at 11am EST (4pm GMT). The presenters, including Clint Pepper and Jeffrey Breit, Directors at Bend Research, a division of Capsugel Dosage Form Solutions, will describe how real time data generation and visualization tools are being used to monitor bioreactor processes in order to enhance cell line and process understanding for research scientists. The session will be moderated by David Lyon, Senior Vice President of Research at Bend Research.


Biopharmaceutical companies are continually striving to fundamentally understand and optimize cellular performance within their bioreactors. While on-line process analytical technology (PAT) tools like dielectric and Raman spectroscopy are helping to provide insight into cell processes that impact titer and antibody quality, the integration of these data with off-line measurements such as cell density, viability, and titer remains an elusive goal.


Bend Research, in collaboration with Pfizer and other major biopharmaceutical companies, continues to advance its Modular Automated Sampling Technology (MAST™) and automated data retrieval and analysis platforms. The ultimate goal of these systems is to enable improved bioreactor productivity and efficiency through effective and real time data generation and management. The overall solution to the end user incorporates aseptically collected bioreactor samples delivered to multiple analytical devices and a graphical user interface (GUI) for real-time data analysis and predictive model development. Early studies with the MAST sample delivery system, coupled with our data-processing software, indicate better system 'observability' and real-time process understanding for the end user, thus setting the stage for optimized process control systems.


The presenters will discuss how Bend Research has created an integrated lab environment, that capitalizes on the MAST platform, to collect high density data sets for on-line analysis and predictive model generation. From this new level of insight into the bioreactor, scientists can obtain enhanced data-driven guidance for key activities, like enhanced process understanding and optimized process operation. With this new technology, the bioprocess industry can make major advances toward innovative real-time testing, predictive control, and overall enhanced bioprocess design and operation.